Our lab is broadly interested in understanding gene and environmental factors that influence organismal physiology with a focus on development, stress response, and aging. We use the nematode worm Caenorhabditis elegans to uncover underlying genetic factors that regulate these processes. In the lab, we use a combination of classic and contemporary genetics with a high-throughput screening approach that allows us to design experiments that may be impossible to carry out in a mammalian system.
In the long term, we hope our research will address several important questions:
- What environmental chemicals exhibit biotoxicity, and how do cells respond to these chemicals?
- How do genes that are affected by environmental stress link to development, aging, and potentially disease phenotypes?
Research supported by
